Litcius/Paper detail

Discovery of new quinoxaline-2(1H)-one-based anticancer agents targeting VEGFR-2 as inhibitors: Design, synthesis, and anti-proliferative evaluation

Khaled El‐Adl, Helmy Sakr, Reda G. Yousef, Ahmed B. M. Mehany, Ahmed M. Metwaly, Mostafa A. Elhendawy, Mohamed M. Radwan, Mahmoud A. ElSohly, Hamada S. Abulkhair, Ibrahim H. Eissa

2021Bioorganic Chemistry108 citationsDOI

Topics & Concepts

SorafenibChemistryDoxorubicinCell cultureIC50PharmacologyDocking (animal)QuinoxalinePaclitaxelCell growthCancer researchIn vitroCancerBiochemistryChemotherapyInternal medicineBiologyMedicineGeneticsOrganic chemistryNursingHepatocellular carcinomaSynthesis and Biological EvaluationBioactive Compounds and Antitumor AgentsSynthesis and biological activity