The Potential Relationship Between Low Back Pain and Depression: A Comprehensive Review
力伟 曹, Biao Deng, Xiaole Wang, Ting Fang, KuyikAbasi Nsima Umoh, Lang Liu, Jiaming Qian, Fushui Liu
Abstract
PURPOSE OF REVIEW: The primary objective of this review is to explore and elucidate the potential relationship between low back pain (LBP) and depression. As both conditions are prevalent health issues affecting a significant portion of the population, understanding their interplay is crucial for developing effective treatment strategies. By examining the existing research, this review aims to provide insights into the biological, psychological, and social factors that contribute to this intricate relationship. RECENT FINDINGS: Recent research has shown an interdependent relationship between LBP and depression. Chronic pain can lead to depression by affecting daily life and work, whereas depression can exacerbate pain perception due to alterations in brain processing. Studies have shown that pain and emotional regulation share the same brain regions, providing a neurobiological basis for their coexistence. Furthermore, psychological factors such as anxiety, stress, and poor coping mechanisms have been shown to have associations with both conditions. SUMMARY: The relationship between LBP and depression is complex and multifaceted. Addressing both the physical and psychological aspects of these conditions is essential for effective management. Interdisciplinary approaches, including pharmacological treatment, psychological therapy, physical therapy, and lifestyle modifications, should be considered to improve outcomes for patients suffering from both LBP and depression.