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A shared neoantigen vaccine combined with immune checkpoint blockade for advanced metastatic solid tumors: phase 1 trial interim results

Amy Rappaport, Chrisann Kyi, Monica Lane, Meghan G. Hart, Melissa L. Johnson, Brian S. Henick, Chih‐Yi Liao, Amit Mahipal, Ardaman Shergill, Alexander I. Spira, Jonathan W. Goldman, Ciaran D. Scallan, Desiree Schenk, Christine D. Palmer, Matthew J. Davis, Sonia Kounlavouth, Lindsey Kemp, Aaron Yang, Y. Li, Molly Likes, Annie Shen, Gregory R. Boucher, Milana Egorova, Robert L. Veres, J. Aaron Espinosa, Jason R. Jaroslavsky, Lauren D. Kraemer Tardif, Lindsey Acrebuche, Christopher Puccia, Leiliane Sousa, Rita Zhou, Kyounghwa Bae, J. Randolph Hecht, David P. Carbone, Benny Johnson, Andrew M. Allen, Andrew R. Ferguson, Karin Jooss

2024Nature Medicine127 citationsDOI

Topics & Concepts

MedicineImmunologyImmune checkpointAdverse effectAntigenImmunotherapyOncologyImmune systemInternal medicineImmunotherapy and Immune ResponsesCancer Immunotherapy and BiomarkersCAR-T cell therapy research