Discovery of metal complexes with antibacterial properties in aqueous extracts of <i>Radix scutellariae</i> and a study of the antibacterial properties of the baicalin–manganese complex
Yafeng Liu, Chenxi Jiang, Peng Liang, Zhimin Li, Jintao Wang, Xiangwen Liao, Wenying Guo
Abstract
In the process of extraction with hot water, many organic components in Radix scutellariae form complexes with metal ions. Among them, baicalin–manganese has good antibacterial activity and less tendency to cause resistance.
Topics & Concepts
BaicalinManganeseRadix (gastropod)ChemistryAntibacterial activityAqueous solutionTraditional medicineMetal ions in aqueous solutionExtraction (chemistry)MetalNuclear chemistryBacteriaChromatographyOrganic chemistryBotanyBiologyHigh-performance liquid chromatographyMedicineGeneticsFlavonoids in Medical ResearchPlant-based Medicinal ResearchPhytochemistry and Biological Activities