Recent Advances in the Chemistry of Isocyanides with Activated Methylene Group
Ilya V. Efimov, Л. Н. Куликова, Dmitry I. Zhilyaev, Leonid G. Voskressensky
Abstract
This review is devoted to the recent advances in the chemistry of methylene isocyanides with C=C, C≡C, C=O, and C=N bonds. In this paper, we show a variety of [3+2] cycloaddition reactions for isocyanides, carried out both under catalytic and non‐catalytic conditions. In addition, we also focused on diastereo‐ and enantioselectivity data.
Topics & Concepts
ChemistryMethyleneCycloadditionCatalysisOrganic chemistryIsocyanideMedicinal chemistryCombinatorial chemistryOrganic Chemistry Cycloaddition ReactionsClick Chemistry and ApplicationsSynthesis and Catalytic Reactions