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Exploring Varied Treatment Strategies for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Amani Elshaer, David M. Chascsa, Blanca Lizaola‐Mayo

2024Life20 citationsDOIOpen Access PDF

Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD) represents a liver disorder characterized by steatosis with underlying metabolic risk factors. The prevalence of MASLD continues to rise, leading to increased patient risk of various complications. Recent research has been focused on new therapeutic strategies to reduce the incidence of MASLD and provide effective treatment plans to prevent further irreversible liver damage. The treatment approach is multifactorial, with a primary focus on weight loss and management of underlying comorbidities through lifestyle modifications, pharmacotherapy, or surgical options. Ongoing research is exploring new pharmacological therapies that could enhance the treatment of MASLD.

Topics & Concepts

MedicineSteatosisIntensive care medicineDiseasePharmacotherapyFatty liverLiver diseaseIncidence (geometry)Lifestyle modificationMetabolic disorderBioinformaticsInternal medicineBiologyPhysicsOpticsLiver Disease Diagnosis and TreatmentDiet, Metabolism, and DiseaseDiet and metabolism studies
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