From monomer to micelle: a facile approach to the multi-step synthesis of block copolymers <i>via</i> inline purification
Pieter‐Jan Voorter, Gayathri Dev, Axel‐Laurenz Buckinx, Jinhuo Dai, Priya Subramanian, Anil Kumar, Neil R. Cameron, Tanja Junkers
Abstract
in-line NMR. The purified reaction mixture can then be chain extended in a second reactor stage to obtain block copolymers using poly(ethylene glycol) methyl ether acrylate (PEGMEA) as the second monomer. In the last step, nano-objects are created, again from flow processes. The process is highly tuneable, showing for the chosen model system a variation in nanoaggregate size from 34 nm to 188 nm.
Topics & Concepts
CopolymerMicelleMonomerBlock (permutation group theory)Materials sciencePolymer chemistryChemical engineeringCombinatorial chemistryChemistryPolymerOrganic chemistryMathematicsEngineeringAqueous solutionGeometryAdvanced Polymer Synthesis and CharacterizationInnovative Microfluidic and Catalytic Techniques InnovationBlock Copolymer Self-Assembly