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Isoflurane Enhances Autophagy by Activating AMPK/ULK1, Inhibits NLRP3, and Reduces Cognitive Impairment After Cerebral Ischemia–Reperfusion Injury in Rats

Jingwen Zhai, Li Nian, Xu Zhang, Yan Li, Ketao Ma, Ruixue Wang, Xinlei Qin, Jiangwen Yin, Sheng Wang

2023Journal of Molecular Neuroscience18 citationsDOI

Topics & Concepts

AMPKAutophagyIsofluraneMedicineIschemiaReperfusion injuryPharmacologyInflammationBrain ischemiaULK1AnesthesiaInternal medicineProtein kinase AChemistryKinaseBiologyApoptosisCell biologyBiochemistryNeuroinflammation and Neurodegeneration MechanismsAutophagy in Disease and TherapyNeurological Disease Mechanisms and Treatments
Isoflurane Enhances Autophagy by Activating AMPK/ULK1, Inhibits NLRP3, and Reduces Cognitive Impairment After Cerebral Ischemia–Reperfusion Injury in Rats | Litcius