Theoretical 13C chemical shift, 14N, and 2H quadrupole coupling–constant studies of hydrogen bonding for measurement and calculation of 13C and 15N NMR chemical–shift tensors in DNA/RNA of gum cancer cells identification: A powerful alternative
Alireza Heidari, Ricardo Gobato, Lauro Figueroa Valverde
Abstract
It cannot be denied that NMR biospectroscopy has several advantages that attribute to this technique a great potential towards viral diagnostic routines. This technique cannot be overlooked, and must be considered a possible alternative for theoretical 13 C chemical shift, 14 N, and 2 H quadrupole coupling-constant studies of hydrogen bonding for measurement and calculation of 13 C and 15 N NMR chemical-shift tensors in DNA/RNA of gum cancer cells identification. Several people die every day for lack of a quick, reliable and relatively inexpensive diagnosis. In conjunction with NMR biospectroscopic analysis, multivariate data analysis provides powerful support for interpretation and pattern recognition. Finally, NMR biospectroscopy approaches combined with multivariate analysis provide a powerful weapon in studies for development of rapid diagnostics, which can be extended to several cancers of different types and strains.