Anti-aging biomaterial sturgeon chondroitin sulfate upregulating anti-oxidant and SIRT-1/c-fos gene expression to reprogram stem cell senescence and prolong longevity
Abhinay Kumar Singh, Bou‐Yue Peng, Shaw-Ting Chien, Chun-Hao Chan, Yue-Hua Deng, H. Pai, Hong-Jian Wei, Ming-Fu Wang, Shwu‐Huey Wang, Chia-Yu Wu, Win‐Ping Deng
Abstract
study, CSDB also restored the aging-phenotype-related bone mineral density and skin morphology to prolong longevity. Thus, sturgeon CSDB may be useful for prolonging healthy longevity as an anti-aging drug.
Topics & Concepts
SenescenceLongevityChondroitin sulfateCell biologyGene expressionStem cellBiomaterialGeneCellBiologyChemistryBiochemistryGlycosaminoglycanGeneticsOrganic chemistrySilk-based biomaterials and applicationsProteoglycans and glycosaminoglycans researchElectrospun Nanofibers in Biomedical Applications