Clinical Relevance of RSV and SARS-CoV-2 Coinfections in Infants and Young Children
Rosa Rodríguez Fernández, Felipe González Martínez, Jimena Pérez-Moreno, María-Isabel González-Sánchez, Blanca Toledo del Castillo, Irene Mingueza de la Paz, L. Pozo, Asunción Mejías, Octavio Ramilo
Abstract
We analyzed the frequency, clinical impact and severity of respiratory syncytial virus (RSV) and SARS-CoV-2 coinfections in a single pediatric center between March 2020 and January 2023. Compared to single RSV infections, RSV/SARS-CoV-2 coinfections were uncommon (2.1%), occurred more frequently during circulation of omicron, and were associated with increased disease severity as defined by longer hospitalization and increased need for high-flow nasal cannula.
Topics & Concepts
MedicineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Nasal cannulaCoinfectionSingle CenterRespiratory systemCoronavirus disease 2019 (COVID-19)PediatricsDisease2019-20 coronavirus outbreakVirologyVirusCannulaInternal medicineSurgeryInfectious disease (medical specialty)OutbreakRespiratory viral infections researchTracheal and airway disordersRespiratory Support and Mechanisms