Synergistic effect of Mn-Si-COS on wound immune microenvironment by inhibiting excessive skin fibrosis mediated with ROS/TGF-β1/Smad7 signal
Yi Xiong, Xiuhong Huang, Yanpeng Jiao, Changren Zhou, Changyuan Yu
Topics & Concepts
FibrosisChemistryInflammationOxidative stressTransforming growth factorSMADDownregulation and upregulationFibroblastImmune systemWound healingSecretionSignal transductionCell biologyCancer researchImmunologyBiologyBiochemistryMedicineInternal medicineIn vitroGeneWound Healing and TreatmentsPeriodontal Regeneration and TreatmentsPressure Ulcer Prevention and Management