RoB 2: a revised tool for assessing risk of bias in randomised trials
Jonathan A C Sterne, Jelena Savović, Matthew J. Page, Roy G. Elbers, Natalie Blencowe, Isabelle Boutron, Christopher J Cates, Hung‐Yuan Cheng, Mark Corbett, Sandra Eldridge, Jonathan Emberson, Miguel A. Hernán, Sally Hopewell, Asbjørn Hróbjartsson, Daniela R. Junqueira, Peter Jüni, Jamie J Kirkham, Toby J Lasserson, Tianjing Li, Alexandra McAleenan, Barnaby C Reeves, Sasha Shepperd, Ian Shrier, Lesley Stewart, Kate Tilling, Ian R. White, Penny Whiting, Julian P. T. Higgins
Abstract
Assessment of risk of bias is regarded as an essential component of a systematic review on the effects of an intervention. The most commonly used tool for randomised trials is the Cochrane risk-of-bias tool. We updated the tool to respond to developments in understanding how bias arises in randomised trials, and to address user feedback on and limitations of the original tool.