Robustness of tissue oxygenation estimates by continuous wave space-resolved near infrared spectroscopy
Caterina Amendola, Davide Contini, Rebecca Re, Lorenzo Spinelli, Lorenzo Frabasile, Pietro Levoni, Alessandro Torricelli
Abstract
Significance: ] and the modeling of tissue as homogeneous. Aim: was varied from expected values, and when layered tissue was considered. Approach: ) and their relative error. Results: when the superficial thickness exceeds 5 mm. Conclusions: These results highlight the need for more sophisticated strategies (e.g., the use of multiple short and long distances) to reduce the influence of superficial tissues in retrieving hemodynamic parameters and warn the SRS users to be aware of the intrinsic limitation of this approach, particularly when exploited in the clinical environment.
Topics & Concepts
Deoxygenated HemoglobinMaterials scienceOxygenationWavelengthSaturation (graph theory)Robustness (evolution)OpticsNuclear magnetic resonanceSpectroscopyNear-infrared spectroscopyScatteringBiomedical engineeringDiffuse optical imagingChemistryAnalytical Chemistry (journal)PhysicsMathematicsHemoglobinTomographyAnesthesiaChromatographyMedicineBiochemistryCombinatoricsQuantum mechanicsGeneOptical Imaging and Spectroscopy TechniquesNon-Invasive Vital Sign MonitoringHemodynamic Monitoring and Therapy