Litcius/Paper detail

Dynamical and numerical analysis of the hepatitis B virus treatment model through fractal–fractional derivative

Wadhah Al-Sadi, Zhouchao Wei, Tariq Abdullah, Abdulwasea Alkhazzan, J. F. Gómez‐Aguilar

2024Mathematical Methods in the Applied Sciences14 citationsDOI

Abstract

Infection with the hepatitis B virus (HBV) is a global health problem and may be controlled via appropriate treatment. We use fractional models to understand infectious diseases because fractional models help us understand treatments' effects on hepatitis B better than integer‐order models. In this article, we introduce a new mathematical model for HBV based on the fractal–fractional derivative with a generalized Mittag–Leffler kernel. Firstly, we discuss the fundamental properties, like the equilibria of the model and the primary reproduction number. Then, we investigate the existence of a unique solution to our model. We use an iterative method to solve the proposed model. Further, we discuss the stability of the model through stability theory. Finally, we offer some graphical illustrations for various values of the parameters.

Topics & Concepts

MathematicsFractalFractional calculusApplied mathematicsStability (learning theory)Integer (computer science)Basic reproduction numberKernel (algebra)Hepatitis B virusHepatitis a virusPure mathematicsMathematical analysisVirusComputer scienceMedicineVirologyMachine learningPopulationEnvironmental healthProgramming languageFractional Differential Equations SolutionsMathematical and Theoretical Epidemiology and Ecology ModelsNonlinear Differential Equations Analysis