Nanoparticle-integrated dissolving microneedles for the co-delivery of R848/aPD-1 to synergistically reverse the immunosuppressive microenvironment of triple-negative breast cancer
Sicong Huang, Ting Wen, Jiachen Wang, Huiye Wei, Zecong Xiao, Bo Li, Xintao Shuai
Topics & Concepts
Tumor microenvironmentCancer researchTriple-negative breast cancerImmunotherapyImmune systemDrug deliveryCD8Cancer immunotherapyBreast cancerMedicineCancerMaterials scienceImmunologyInternal medicineNanotechnologyImmunotherapy and Immune ResponsesCancer Immunotherapy and BiomarkersImmune Cell Function and Interaction