Impacts of particle size on the cytotoxicity, cellular internalization, pharmacokinetics and biodistribution of betulinic acid nanosuspensions in combined chemotherapy
Ruoning Wang, Xin Wang, Xiaoshun Jia, Honglan Wang, Wen Li, Junsong Li
Topics & Concepts
InternalizationEndocytosisCytotoxicityBioavailabilityBetulinic acidBiodistributionPinocytosisChemistryIn vivoParticle sizeIn vitroBiophysicsPharmacologyBiochemistryCellBiologyGeneticsBiotechnologyPhysical chemistryNatural product bioactivities and synthesisPlant biochemistry and biosynthesisGlycosylation and Glycoproteins Research