Modified cyclodextrins solubilize elemental sulfur in water and enable biological sulfane sulfur delivery
Sarah G. Bolton, Michael D. Pluth
Abstract
Sulfane sulfur, or S <sup>0</sup> , is found in polysulfide and persulfide compounds in biology. We demonstrate that modified cyclodextrins can solubilize S <sub>8</sub> in water, increase its reactivity with biological nucleophiles, and enable delivery to live cells.
Topics & Concepts
PolysulfideSulfurNucleophileSolubilizationReactivity (psychology)ChemistryCombinatorial chemistryOrganic chemistryBiochemistryPathologyAlternative medicinePhysical chemistryElectrodeMedicineCatalysisElectrolyteSulfur Compounds in BiologyGenomics, phytochemicals, and oxidative stressRedox biology and oxidative stress