Succinate drives gut inflammation by promoting FOXP3 degradation through a molecular switch
Hai Wang, Danqing Hu, Cheng Yang, Qiong Gao, Kun Liu, Nikita Mani, Amy Tang, Radhika Iyer, Beixue Gao, Leyu Sun, Qi Zhou, Qin Yu, Samuel E. Weinberg, Xiaoyu Zhang, Yingzi Cong, Parambir S. Dulai, Yana Zhang, Zheng Liu, Deyu Fang
Topics & Concepts
InflammationDegradation (telecommunications)Cell biologyFOXP3ChemistryBiologyImmunologyImmune systemComputer scienceTelecommunicationsImmune Cell Function and InteractionT-cell and B-cell ImmunologyInflammasome and immune disorders