Allopurinol hypersensitivity syndrome
Wid Yaseen, Bourne L. Auguste, Jonathan S. Zipursky
Abstract
Allopurinol hypersensitivity syndrome includes Stevens–Johnson syndrome, toxic epidermal necrolysis and drug reaction with eosinophilia and systemic symptoms. It affects about 1 in 1000 patients prescribed allopurinol, and reported mortality is between 20% and 25%.[1][1] Patients typically present
Topics & Concepts
AllopurinolToxic epidermal necrolysisMedicineEosinophiliaDermatologyHypersensitivity reactionDrugInternal medicinePharmacologyDrug-Induced Adverse ReactionsEosinophilic Disorders and SyndromesGout, Hyperuricemia, Uric Acid