Adalimumab in the Management of Isotretinoin-Induced Acne Fulminans: Report of a Case
Claudio Marasca, Gabriella Fabbrocini, Luisa Abategiovanni, Elisa Camela, Mariateresa Nocerino, Adriana Di Guida, Gaia De Fata Salvatores
Abstract
Acne fulminans (AF) is a rare, acute, and severe form of acne vulgaris often associated with systemic symptoms. Its treatment is challenging and controversial. We report a case of isotretinoin-induced AF (IIAF) in a 12-year-old boy resistant to traditional therapies (oral steroids and isotretinoin). The patient was successfully treated with adalimumab that can be considered an effective off-label option in the treatment of resistant IIAF in children.
Topics & Concepts
IsotretinoinMedicineAcneAdalimumabDermatologyInternal medicineDiseaseAcne and Rosacea Treatments and EffectsHidradenitis Suppurativa and TreatmentsOral Health Pathology and Treatment