Litcius/Paper detail

Muscone relieves inflammatory pain by inhibiting microglial activation-mediated inflammatory response via abrogation of the NOX4/JAK2-STAT3 pathway and NLRP3 inflammasome

Shanshan Yu, Guoqing Zhao, Fanglei Han, Wenzhao Liang, Jiao Yuan, Zinan Li, Longyun Li

2020International Immunopharmacology75 citationsDOI

Topics & Concepts

InflammasomeMicrogliaInflammationSTAT3NOX4Pyrin domainMedicineSTAT proteinNADPH oxidasePharmacologyChemistryImmunologySignal transductionReactive oxygen speciesBiochemistryPain Mechanisms and TreatmentsPharmacological Effects of Natural CompoundsNeuroinflammation and Neurodegeneration Mechanisms
Muscone relieves inflammatory pain by inhibiting microglial activation-mediated inflammatory response via abrogation of the NOX4/JAK2-STAT3 pathway and NLRP3 inflammasome | Litcius