Mixed-mode separation of antisense oligonucleotides using a single column with complementary anion-exchange and hydrophobic interaction chromatography approaches
Artaches A. Kazarian, Jung Hwa Lee, Branko Mitasev, Hyeong-Wook Choi
Topics & Concepts
ChemistryChromatographyOligonucleotideHydrophilic interaction chromatographyIon exchangeIon chromatographyColumn (typography)IonHigh-performance liquid chromatographyDNAOrganic chemistryBiochemistryConnection (principal bundle)Structural engineeringEngineeringDNA and Nucleic Acid ChemistryAnalytical Chemistry and ChromatographyAdvanced biosensing and bioanalysis techniques