Nuclear translocation of ASPL-TFE3 fusion protein creates favorable metabolism by mediating autophagy in translocation renal cell carcinoma
Ru Fang, Xiaotong Wang, Qiuyuan Xia, Ming Zhao, Hao Zhang, Xuan Wang, Shengbing Ye, Kai Cheng, Liang Yan, Yang Cheng, Yayun Gu, Qiu Rao
Topics & Concepts
AutophagyBiologyChromosomal translocationFusion proteinPI3K/AKT/mTOR pathwayTFE3Cancer researchTFEBCell biologyMechanistic target of rapamycinSignal transductionGeneticsGeneTranscription factorApoptosisEnhancerRecombinant DNAAutophagy in Disease and TherapyEndoplasmic Reticulum Stress and DiseaseUbiquitin and proteasome pathways