Mir-22-incorporated polyelectrolyte coating prevents intima hyperplasia after balloon-induced vascular injury
Jia-Yin Fu, Yu-xian Lai, Si-si Zheng, Jing Wang, Youxiang Wang, Ke‐feng Ren, Lu Yu, Guosheng Fu, Jian Ji
Abstract
the miR-22-methyl-CpG binding protein 2 (MECP2) axis. Our findings indicate that balloons coated with PEI/PAA/miR-22 have great potential to be promising DCBs in the treatment of cardiovascular disease.
Topics & Concepts
RestenosisIn vivoPolyacrylic acidIntimal hyperplasiaChemistryCoatingVascular smooth musclePolyelectrolyteBiophysicsMedicineSurgerySmooth muscleBiologyInternal medicinePolymerStentOrganic chemistryBiotechnologyCoronary Interventions and DiagnosticsAngiogenesis and VEGF in CancerElectrospun Nanofibers in Biomedical Applications