The Use of MR-Guided Radiation Therapy for Pancreatic Cancer
Lois A. Daamen, Parag J. Parikh, William A. Hall
Abstract
The introduction of online adaptive magnetic resonance (MR)-guided radiation therapy (RT) has enabled safe treatment of pancreatic cancer with ablative doses. The aim of this review is to provide a comprehensive overview of the current literature on the use and clinical outcomes of MR-guided RT for treatment of pancreatic cancer. Relevant outcomes included toxicity, tumor response, survival and quality of life. The results of these studies support further investigation of the effectiveness of ablative MR-guided SBRT as a low-toxic, minimally-invasive therapy for localized pancreatic cancer in prospective clinical trials.
Topics & Concepts
MedicinePancreatic cancerRadiation therapyAblative caseClinical trialMagnetic resonance imagingCancerRadiologyOncologyMedical physicsInternal medicinePancreatic and Hepatic Oncology ResearchMRI in cancer diagnosisRadiation Therapy and Dosimetry