Glucocorticoid-induced osteoporosis: Insights for the clinician
Shakaib Hayat, Marina Magrey
Abstract
Glucocorticoids cause significant bone loss, predominantly affecting trabecular bone, with consequent fragility fractures. The risk of fractures is related to the dose and duration of glucocorticoid use, but an increased risk may be observed even at low doses and even in the first month of treatment. Steps to prevent or treat osteoporosis should be considered in all patients who take the equivalent of prednisone at a dose of 2.5 mg or more per day for 3 or more months.
Topics & Concepts
MedicineOsteoporosisGlucocorticoidPrednisoneFragility fractureInternal medicineEndocrinologyBone mineralBone health and osteoporosis researchAdrenal Hormones and DisordersBone health and treatments