Litcius/Paper detail

Controlled reductive C–C coupling of isocyanides promoted by an aluminyl anion

Matthew J. Evans, Mathew D. Anker, Claire L. McMullin, Martyn P. Coles

2023Chemical Science18 citationsDOIOpen Access PDF

Abstract

Controlled addition of isocyanides R-NC to a potassium aluminyl afforded the C2- and C3- homologized products.

Topics & Concepts

IonCoupling (piping)Reductive eliminationChemistryCombinatorial chemistryIsocyanideComputational chemistryStereochemistryMaterials scienceOrganic chemistryCatalysisMetallurgyCatalytic Cross-Coupling ReactionsCatalytic C–H Functionalization MethodsOrganoboron and organosilicon chemistry