Phillygenin ameliorates nonalcoholic fatty liver disease via TFEB-mediated lysosome biogenesis and lipophagy
Wenling Zhou, Xu Yan, Yuanyuan Zhai, Hao Liu, Lingling Guan, Yuan Qiao, Jizhi Jiang, Liang Peng
Topics & Concepts
TFEBAutophagyNonalcoholic fatty liver diseaseCell biologyLipid dropletLysosomeHepatocyteSteatosisChemistryBiologyFatty liverEndocrinologyInternal medicineBiochemistryMedicineIn vitroApoptosisDiseaseEnzymeAutophagy in Disease and TherapyLiver Disease Diagnosis and TreatmentPlant-derived Lignans Synthesis and Bioactivity