Mac1-Dependent Copper Sensing Promotes <i>Histoplasma</i> Adaptation to the Phagosome during Adaptive Immunity
Stephanie C. Ray, Chad A. Rappleye
Abstract
Histoplasma capsulatum is a fungal pathogen that survives and grows within host macrophages. For successful infection, Histoplasma must sense and adapt to a dynamic intracellular environment over the course of an infection.
Topics & Concepts
PhagosomeHistoplasmaImmunityAcquired immune systemAdaptation (eye)MicrobiologyHistoplasma capsulatumBiologyImmune systemHistoplasmosisVirologyImmunologyPhagocytosisNeuroscienceAntimicrobial Peptides and ActivitiesFungal Infections and StudiesStudies on Chitinases and Chitosanases