A <i>de novo</i> dual-targeting supramolecular self-assembly peptide against pulmonary metastasis of melanoma
Jingjing Wang, Xiaoqiang Zheng, Xiao Fu, Aimin Jiang, Yu Yao, Wangxiao He
Abstract
In summary, a supramolecular peptide-based strategy was not only developed to suppress pulmonary metastasis of melanoma, but it also renewed efforts to identify cocktail drugs that act on intracellular targets in various human diseases, including cancer.
Topics & Concepts
MelanomaMAPK/ERK pathwayCancer researchMetastasisWnt signaling pathwayTargeted therapyMedicinePeptideSurgical oncologyCancerChemistryBiologySignal transductionCell biologyInternal medicineBiochemistryPeptidase Inhibition and AnalysisChemical Synthesis and AnalysisCancer Mechanisms and Therapy