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Structure of the ciliary tip central pair reveals the unique role of the microtubule-seam binding protein SPEF1

Thibault Legal, Ewa Joachimiak, Mireya Parra, Wang Peng, Amanda Tam, Corbin Black, Mayukh Guha, Chau Anh Nguyen, Avrin Ghanaeian, Melissa Valente-Paterno, Gary J. Brouhard, Jacek Gaertig, Dorota Włoga, Khanh Huy Bui

2025Current Biology16 citationsDOI

Topics & Concepts

MicrotubuleCiliumBiologyAxonemeTubulinCell biologyTetrahymenaMicrotubule nucleationMicrotubule-associated proteinBasal bodyBiophysicsFlagellumCentrosomeBiochemistryCellCell cycleGeneMicrotubule and mitosis dynamicsGenetic and Kidney Cyst DiseasesProtist diversity and phylogeny
Structure of the ciliary tip central pair reveals the unique role of the microtubule-seam binding protein SPEF1 | Litcius