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Acceptorless Dehydrogenative Coupling Reactions by Manganese Pincer Complexes

Pinaki Nad, Arup Mukherjee

2021Asian Journal of Organic Chemistry54 citationsDOI

Abstract

Abstract Acceptorless dehydrogenative coupling reactions has emerged as one of the promising technique in synthetic organic chemistry to construct carbon‐carbon and carbon‐heteroatom bonds in an environmentally benign and sustainable way. The methodology is highly atom economical and produces water and hydrogen as the byproducts. This protocol, coupled with the earth‐abundant and less toxic manganese catalyst provides a unique opportunity to construct various synthons and biologically important motifs. In recent years, tremendous progress has been made with manganese catalysis based on the pincer ligands for various homogeneous transformations. This review covers the recent progress in the field of manganese catalyzed acceptorless dehydrogenative coupling reactions, their scope and brief mechanistic discussion.

Topics & Concepts

ChemistryManganeseSynthonHeteroatomPincer movementCatalysisCombinatorial chemistryAtom economyDehydrogenationHomogeneous catalysisCarbon fibersGreen chemistryOrganic chemistryReaction mechanismMaterials scienceRing (chemistry)Composite materialComposite numberAsymmetric Hydrogenation and CatalysisCatalytic C–H Functionalization MethodsCarbon dioxide utilization in catalysis