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Single cell RNA sequencing detects persistent cell type- and methylmercury exposure paradigm-specific effects in a human cortical neurodevelopmental model

M. Diana Neely, Shaojun Xie, Lisa M. Prince, Hyunjin Kim, Anke M. Tukker, Michael Aschner, Jyothi Thimmapuram, Aaron B. Bowman

2021Food and Chemical Toxicology30 citationsDOIOpen Access PDF

Topics & Concepts

MethylmercuryInduced pluripotent stem cellBiologyHuman brainCellCell typePopulationNeuroscienceGene expressionNeural stem cellCell growthRNAEmbryonic stem cellGeneCell biologyStem cellGeneticsMedicineEcologyEnvironmental healthBioaccumulationMercury impact and mitigation studiesSingle-cell and spatial transcriptomicsAdvanced biosensing and bioanalysis techniques
Single cell RNA sequencing detects persistent cell type- and methylmercury exposure paradigm-specific effects in a human cortical neurodevelopmental model | Litcius