Modulation of histone deacetylase, the ubiquitin proteasome system, and autophagy underlies the neuroprotective effects of venlafaxine in a rotenone-induced Parkinson's disease model in rats
Khalid A El-Saiy, Rabab H. Sayed, Ayman E. El-Sahar, Esraa A. Kandil
Topics & Concepts
NeuroprotectionAutophagyHistone deacetylaseHDAC4Parkinson's diseaseHDAC6RotenonePharmacologyDopamineBiologyChemistryCell biologyNeuroscienceHistoneMedicineInternal medicineMitochondrionBiochemistryApoptosisDiseaseGeneParkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and TherapyHistone Deacetylase Inhibitors Research