Gut microbiota-derived 3-indoleacetic acid confers a protection against sepsis-associated encephalopathy through microglial aryl hydrocarbon receptors
Huang Zhi-bin, Guo-Pan Zhang, Chen-Xin Lu, Cansheng Gong, Xia Gao, Yanqi Lin, Ping Su, Wenyan Xu, Yongbao Lin, Na Lin, Xuyang Wu, Xiaohui Chen, Ting Zheng, Xiaochun Zheng
Topics & Concepts
Aryl hydrocarbon receptorSepsisPathogenesisGut floraEncephalopathyReceptorOxidative stressMicrogliaMicrobiologyGut–brain axisBacteriaBiologyCentral nervous systemImmunologyInflammationChemistryMedicineNeuroscienceBiochemistryInternal medicineGeneTranscription factorGeneticsGut microbiota and healthNeuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders