Suzuki–Miyaura cross-coupling of esters by selective O–C(O) cleavage mediated by air- and moisture-stable [Pd(NHC)(μ-Cl)Cl]<sub>2</sub>precatalysts: catalyst evaluation and mechanism
Shiyi Yang, Tongliang Zhou, Albert Poater, Luigi Cavallo, Steven P. Nolan, Michal Szostak
Abstract
precatalysts on several levels, including facile one-pot synthesis, superior atom-economic profile to all other Pd(II)-NHC catalysts, and versatile reactivity, these should be considered as the 'first-choice' catalysts for all routine applications in ester O-C(O) bond activation.
Topics & Concepts
CatalysisCleavage (geology)ArylChemistryMoistureCoupling (piping)Combinatorial chemistryMedicinal chemistryPolymer chemistryOrganic chemistryMaterials scienceAlkylMetallurgyFracture (geology)Composite materialCatalytic Cross-Coupling ReactionsCatalytic C–H Functionalization MethodsRadical Photochemical Reactions