DR5-targeted, chemotherapeutic drug-loaded nanoparticles induce apoptosis and tumor regression in pancreatic cancer in vivo models
Michael C. Johnston, Julie A. Nicoll, Kelly M. Redmond, Peter Smyth, Michelle K. Greene, William J. McDaid, Darren K.W. Chan, Nyree Crawford, Katie J. Stott, Jennifer Fox, Ninfa L. Straubinger, Sandra Roche, Martin Clynes, Robert M. Straubinger, Daniel B. Longley, Christopher J. Scott
Topics & Concepts
FADDCamptothecinPancreatic cancerIn vivoApoptosisCancer researchCaspase 8Pancreatic tumorChemistryFlipTopoisomerasePharmacologyCancerIn vitroCaspase 3Programmed cell deathBiologyCaspaseMedicineInternal medicineBiochemistryBiotechnologyCell death mechanisms and regulationCancer therapeutics and mechanismsPancreatic and Hepatic Oncology Research