Astringent Gallic Acid in Red Wine Regulates Mechanisms of Gastric Acid Secretion via Activation of Bitter Taste Sensing Receptor TAS2R4
Sonja Sterneder, Verena Stoeger, Celina A. Dugulin, Kathrin Liszt, Antonella Di Pizio, Karin Korntheuer, Andreas Dunkel, Reinhard Eder, Jakob P. Ley, Veronika Somoza
Abstract
. These results demonstrate a functional role of TAS2R4 in GA-evoked PS as a key mechanism of gastric acid secretion aiding digestion. Moreover, our data provide mechanistic insights, which will help to produce stomach-friendly red wines.
Topics & Concepts
WineGallic acidTasteSecretionChemistryGastric acidBitter tasteBiochemistryFood scienceAntioxidantBiochemical Analysis and Sensing TechniquesOlfactory and Sensory Function StudiesAdvanced Chemical Sensor Technologies