Synthesis and biological evaluation of 1,2,4-triazole derivatives as potential Nrf2 activators for the treatment of cerebral ischemic injury
Yaoqiang Lao, Yang Wang, Jianwen Chen, Ping Huang, Ruiqi Su, Jinguo Shi, Caibao Jiang, Jingxia Zhang
Topics & Concepts
ChemistryNeuroprotectionPharmacologyHeme oxygenaseReactive oxygen speciesGlutathioneBiochemistryHemeEnzymeMedicineGenomics, phytochemicals, and oxidative stressFree Radicals and AntioxidantsSirtuins and Resveratrol in Medicine