High-intensity interval versus moderate-intensity continuous cycling training in Parkinson’s disease: a randomized trial
Muhammad M. Kathia, Sergiu‐Gabriel Duplea, Julian C. Bommarito, Avery Hinks, Elira Leake, Julia Shannon, Jenna Pitman, Pardeep K Khangura, Alexandra M. Coates, Joshua T. Slysz, Carlin Katerberg, Devin G. McCarthy, Taylor Beedie, Rhianna Malcolm, Leslie Anne Witton, Barbara S. Connolly, Jamie F. Burr, Lori Ann Vallis, Geoffrey A. Power, Philip J. Millar
Abstract
The optimal exercise prescription to improve cardiorespiratory fitness and disease-related motor symptoms in adults with Parkinson’s disease remains unknown. In a single-center randomized trial consisting of either 10 wk of high-intensity interval training (HIIT) or moderate-intensity continuous training (MICT), we found that both training modes increased V̇o 2peak , with a larger clinically meaningful difference following HIIT. Both exercise modes improved motor symptoms and subjective fatigue, whereas HIIT increased the muscular endurance of the knee extensors.