Rational genome and metabolic engineering of Candida viswanathii by split CRISPR to produce hundred grams of dodecanedioic acid
Nam Ngoc Pham, Chin-Wei Chang, Yi‐Hao Chang, Yi Tu, June-Yen Chou, Hsing-Yun Wang, Yu‐Chen Hu
Topics & Concepts
CRISPRMetabolic engineeringGenome engineeringCRISPR interferenceMetabolic pathwayBiologyGeneSynthetic biologyComputational biologyBiotransformationCas9Genome editingEnzymeGenomeBiochemistryCRISPR and Genetic EngineeringMicrobial Metabolic Engineering and BioproductionRNA and protein synthesis mechanisms