Biodistribution and dosimetry in human healthy volunteers of the PET radioligands [11C]CHDI-00485180-R and [11C]CHDI-00485626, designed for quantification of cerebral aggregated mutant huntingtin
Aline Delva, Michel Koole, Kim Serdons, Guy Bormans, Longbin Liu, Jonathan Bard, Vinod Khetarpal, Celia Dominguez, Ignacio Muñoz-Sanjuán, Andrew Wood, Mette Skinbjerg, Yuchuan Wang, Wim Vandenberghe, Koen Van Laere
Topics & Concepts
BiodistributionNuclear medicineDosimetryMedicineEffective dose (radiation)PharmacokineticsIn vivoPharmacologyBiologyBiotechnologyGenetic Neurodegenerative DiseasesMedical Imaging Techniques and ApplicationsAmyotrophic Lateral Sclerosis Research