Evolving cryo-EM structural approaches for GPCR drug discovery
Xin Zhang, Rachel M. Johnson, Ieva Drulyte, Lingbo Yu, Abhay Kotecha, Radostin Danev, Denise Wootten, Patrick M. Sexton, Matthew J. Belousoff
Topics & Concepts
G protein-coupled receptorDrug discoveryCryo-electron microscopyComputational biologyDrugStructural biologyNanotechnologyBiophysicsBiologyReceptorChemistryComputer scienceBioinformaticsMaterials scienceCell biologyBiochemistryPharmacologyReceptor Mechanisms and SignalingMonoclonal and Polyclonal Antibodies ResearchMass Spectrometry Techniques and Applications