Metal‐Free Synthesis of Aryl Selenocyanates and Selenaheterocycles with Elemental Selenium
Xue Zhang, Xiaobo Huang, Yunbing Zhou, Miaochang Liu, Huayue Wu
Abstract
This work reports a green method for the synthesis of aryl selenocyanates via a three-component reaction of arylboronic acids, Se powder, and trimethylsilyl cyanide (TMSCN) under metal-free and additive-free conditions. Remarkably, TMSCN acts as not only the substrate, but also the catalyst. Various selenaheterocycles can be also accessed with a catalytic amount of TMSCN.
Topics & Concepts
Trimethylsilyl cyanideArylSeleniumCatalysisChemistryCyanideOrganic chemistrySubstrate (aquarium)MetalTrimethylsilylAlkylGeologyOceanographyOrganoselenium and organotellurium chemistrySulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods