GPX4-AUTAC induces ferroptosis in breast cancer by promoting the selective autophagic degradation of GPX4 mediated by TRAF6-p62
Rong Gong, Xiaoya Wan, Shilong Jiang, Yidi Guan, Yi‐Zhi Li, Ting Jiang, Zonglin Chen, Changxin Zhong, Linhao He, Zhongyuan Xiang, Junya Yang, Biao Xu, Jin‐Ming Yang, Yan Cheng
Topics & Concepts
AutophagyGPX4Degradation (telecommunications)Breast cancerCancer researchChemistryInternal medicineCancerMedicineApoptosisBiochemistryEngineeringOxidative stressGlutathione peroxidaseTelecommunicationsCatalaseCancer-related gene regulationFerroptosis and cancer prognosisRNA modifications and cancer