Interferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor
Olusegun O. Onabajo, Abdul Rouf Banday, Megan L. Stanifer, Wusheng Yan, Adeola Obajemu, Deanna M. Santer, Oscar Flórez-Vargas, Helen Piontkivska, Joselin M. Vargas, Timothy J. Ring, Carmon Kee, Patricio Doldan, D. Lorne Tyrrell, Juan L. Mendoza, Steeve Boulant, Ludmila Prokunina‐Olsson
Topics & Concepts
BiologyGene isoformInterferonVirologyTMPRSS2CoronavirusInterferon type IInterferon-stimulated geneVirusReceptorGeneCoronavirus disease 2019 (COVID-19)GeneticsInnate immune systemInfectious disease (medical specialty)DiseasePathologyMedicineSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesCancer Immunotherapy and Biomarkers