Facile and scalable fabrication of exosome-mimicking nanovesicles through PEGylated lipid detergent-aided cell extrusion
Jeong Yi Kang, Bo Kyeong Yoon, Hwira Baek, Yuri Ko, Suk Ho Bhang, Joshua A. Jackman, Jin Woong Kim
Abstract
-aided cell extrusion process broadly applies to various cell lines; hence, it could be helpful in the production of ENVs for tissue regeneration, drug delivery, and cancer nanomedicine.
Topics & Concepts
ExtrusionLipid bilayerMaterials scienceMembraneNanomedicineBiophysicsPhospholipidCell membraneDrug deliveryNanotechnologyCellChemistryNanoparticleBiochemistryBiologyComposite materialExtracellular vesicles in diseaseRNA Interference and Gene DeliveryLipid Membrane Structure and Behavior