Design, synthesis, biological evaluation and molecular docking study of novel pyridoxine–triazoles as anti-Alzheimer's agents
Tiyas Pal, Saipriyanka Bhimaneni, Abha Sharma, S.J.S. Flora
Abstract
predictions were also performed to predict toxicity and ADME properties of the molecule 5i and found within drug likeness range. Therefore, 5i could be a promising multi-functional compound that can be used for further development of novel drug for Alzheimer disease.
Topics & Concepts
Docking (animal)PyridoxineChemistryCombinatorial chemistryComputational biologyPharmacologyBiochemistryBiologyMedicineNursingClick Chemistry and ApplicationsSynthesis and biological activitySynthesis and Characterization of Heterocyclic Compounds