Litcius/Paper detail

Isolated Kratom Use Disorder Treated With Extended-Release Buprenorphine Taper

Benjamin Swart, Charles Reznikoff, Katie Steen

2024Journal of Addiction Medicine10 citationsDOI

Abstract

ABSTRACT: This case report highlights a 36-year-old male without history of psychiatric disease, chronic pain, or substance use disorder who developed severe substance use disorder per Diagnostic and Statistical Manual of Mental Disorders , Fifth Edition criteria to kratom. He was successfully treated with sublingual buprenorphine after a 3-year period of intermittent withdrawal management and trials of oral and extended-release injectable naltrexone. After a period of abstinence from kratom, he was tapered from buprenorphine using 2 monthly injections of 100 mg extended-release buprenorphine. His case underscores some of the current uncertainties around kratom use disorder diagnosis and treatment.

Topics & Concepts

BuprenorphineMedicineNaltrexoneAbstinenceOpioid use disorderPsychiatrySubstance abuseInternal medicineOpioidReceptorAlkaloids: synthesis and pharmacologyTraditional and Medicinal Uses of AnnonaceaeChemical synthesis and alkaloids